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Research Associate/Fellow (Fixed term)

School of Medicine, Translational Medical Sciences, Cancer and Stem Cells

Location:  University Park
Salary:  £28,762 to £33,314 per annum (pro rata if applicable) depending on skills and experience (minimum £32348 with relevant PhD).
Closing Date:  Thursday 09 February 2023
Reference:  MED608622

This is an Innovate UK funded post in partnership with an external biotech partner. The aim of the project is to develop an in vitro 3D brain tumour co-culture model. The post holder will use this to test and investigate novel immunomodulators of the tumour microenvironment as cancer therapeutics. Candidates must hold a PhD (or be near to completion of a PhD or equivalent) in cancer biology, tumour immunology, tumour microenvironment or related area. Candidate should also have experience of a range of techniques, with a focus on 3D cell culture models, tumour-immune cell co-culture, flow cytometry and western blotting. The position will involve immunohistochemistry, RNA-SEQ, and reverse phase protein arrays. It would be advantageous to have experience of in vitro 3D co-culture model development, cell signalling, immune checkpoint inhibitors, glioblastomas, and a good understanding of tumour hypoxia and acidosis. You will work within a highly skilled, collaborative and exciting research team, focussing on developing novel approaches to targeting the therapy-resistant hypoxic and acidic regions frequently found within tumours.

This full time post (36.25 hours per week) is available to 29th February 2024. Job share arrangements may be considered.

Informal enquiries may be addressed to Dr Alan McIntyre, tel: 0115 823 1547 or email Please note that applications sent directly to this email address will not be accepted.

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