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Research Associate/Fellow (Fixed term)

Area
Life Sciences

Location
University Park

Salary
£30,487 to £45,585 per annum (pro rata if applicable) depending on skills and experience (minimum £33966 with relevant PhD). Salary progression beyond this scale is subject to performance.

Closing Date
Thursday 04 July 2024

Reference
MED227124

Applications are invited to the above role to support the principal investigator Professor Paul Dyer in conducting research in the area of fungal biology, specifically the evolution and detection of antifungal resistance in the opportunistic pathogen Aspergillus fumigatus. This post is part of a multinational Medical Research Council (UK) and JPIAMR funded project involving academic and medical collaborative partners in the UK, continental Europe and Africa with the aim of improving the detection and diagnosis of emerging antimicrobial resistance. The post will use a combination of classical, genomic, molecular and bioinformatic techniques to investigate the genetic basis of evolution of antifungal resistance in Aspergillus fumigatus, a principal cause of aspergillosis disease in humans, and design diagnostic tools for its detection. The post holder will be expected to undertake independent research as well as working as part of a team. This will include using approaches or methodologies and techniques appropriate to the type of research, and they will be responsible for writing up their work in order to contribute to published outcomes.

The role holder will have the opportunity to use their initiative and creativity to identify areas for research, develop research methods and extend their research portfolio

Candidates must hold a PhD, or be near to submission of a PhD, in a relevant field. They must understand microbial laboratory practices and have existing skills in microbial culture of fungi. They must be familiar with molecular biology techniques (e.g. DNA and RNA extraction, electrophoresis, PCR and qRT-PCR) including transformation and possess bioinformatic skills. Previous experience of working with filamentous fungi and/or Aspergillus species, is highly desirable. 

This full-time (36.25 hour), fixed-term role is available from 1st July 2024 for 36 months, if the start date is delayed this role must end on 30th June 2027. Job share arrangements may be considered.

Informal enquiries may be addressed Paul Dyer at paul.dyer@nottingham.ac.uk. Please note that applications sent directly to this E-mail address will not be accepted.
For background to the work please see: doi:10.3390/jof6040258, doi: 10.1038/nature07528, doi.org/10.1016/j.fbr.2020.10.003, doi:10.1371/journal.pbio.3002278, nature.com/articles/s41564-022-01091-2.

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